SANTA CLARA, CA, May 8, 2025 – At CadenceLIVE Silicon Valley 2025, Cadence introduced the Millennium M2000 Supercomputer as part of its expanded Millennium Enterprise Platform. Powered by NVIDIA Blackwell systems, it supports AI-driven simulation for engineering and drug design.
The new supercomputer integrates Cadence’s solvers with NVIDIA HGX B200 systems, RTX PRO 6000 Blackwell Server GPUs, and CUDA-X libraries to support faster simulation workflows. It enables performance improvements and reduced power use for electronic design automation (EDA), system design and analysis (SDA), and drug discovery applications. The integrated hardware-software stack is designed to improve simulation speed and efficiency, supporting physical AI design and drug development.
“The Millennium M2000 Supercomputer will drive the next leap in AI-accelerated engineering by leveraging our massively scalable solvers, dedicated NVIDIA Blackwell-accelerated computing and AI to help designers continue to push the limits of what is possible,” said Anirudh Devgan, president and CEO of Cadence. “Purpose-built for the most advanced AI models of today and tomorrow, the Millennium M2000 Supercomputer delivers unprecedented designer productivity to propel the next generation of AI infrastructure, physical AI systems and drug discovery.”
“From biology to chip design, the world’s most complex engineering challenges require simulation at scales and speeds only possible with accelerated computing,” said Jensen Huang, founder and CEO of NVIDIA. “Built with NVIDIA Blackwell, CUDA-X and Cadence’s computational software, the Millennium M2000 Supercomputer is a new class of infrastructure: an AI factory for science to drive breakthroughs that will transform discovery across disciplines.”
The next generation of infrastructure AI, physical AI, and scientific AI requires scalable compute resources across data centers and edge devices. Building on the Millennium M1 which is optimized for performance and energy efficiency in CFD simulations, the new Millennium M2000 Supercomputer integrates Cadence’s EDA, SDA, and molecular solvers to support complex simulations in semiconductor and 3D-IC design, digital twins for data centers, and drug modeling. It addresses compute needs across in automotive, aerospace, defense, and hyperscale infrastructure.
Advancing Semiconductors and 3D-IC Design
The Millennium M2000 Supercomputer is the first emulator designed for AI design. It combines all the multiphysics capabilities needed to analyze and optimize 3D-IC and advanced packaging designs, including power, thermal, stress/warpage, and electromagnetics. This reduces the time needed for analysis while maintaining quality. Engineering teams can improve reliability and efficiency in their product development cycles. For example, traditional semiconductor chip-level power integrity simulations cover only small windows of time. With one Millennium M2000 Supercomputer, simulations that used to take hundreds of CPUs nearly two weeks can now be completed in less than a day.
Accelerating Autonomous System Design
The AI infrastructure buildout requires an investment in data centers and compute infrastructure. Energy- and resource-efficient execution is key to enabling next-gen AI foundation models from AI factories. Digital twins improve operational efficiencies, reduce risk and lower total power consumption. The Millennium M2000 Supercomputer accelerates the design and operation of these data center digital twins, and the modeling process required for the racks, boards and equipment that power them.
The Millennium M2000 Supercomputer supports virtual simulations of machines that use AI outside data centers, including autonomous vehicles, drones, and robots. Designing these systems benefits from combining faster computing with specialized software. This approach speeds up the process by creating virtual wind tunnels that mimic real-world conditions with high accuracy. Engineers working on electronic and mechatronic systems can make decisions in less than a day, rather than in several days. This saves both time and energy compared to using a CPU-based Top 500 supercomputer cluster with hundreds of thousands of processors.
Advancing Life Science Innovation
Pharmaceutical researchers are under constant pressure to speed up drug discovery without compromising accuracy. One way to do that is by running simulations efficiently – and that’s where the Millennium M2000 Supercomputer comes in. Using it, Cadence Molecular Sciences enables teams to carry out complex molecular simulations much faster than before. Their Orion Molecular Design Platform, which runs on Cadence OnCloud and is backed by the M2000’s compute power, gives researchers the tools to explore potential drug candidates at a quicker pace. What stands out here is not just speed, but the ability to evaluate more design options within tight timelines. This allows researchers to complete more iterations, decide sooner, and stay on schedule.
Availability and Customer Endorsements
The Millennium M2000 Supercomputer is available both in the cloud and as an on-premises appliance. Multiple customers have provided endorsements, including Ascendance, Boom Supersonic, MediaTek, Supermicro and Treeline Biosciences, which can be viewed in the quote sheet.
Source: Cadence
About Cadence
Cadence Design Systems, Inc. is a U.S.-based technology company specializing in electronic design automation (EDA) software, hardware, and intellectual property (IP) solutions. Founded in 1988 through the merger of SDA Systems and ECAD, Cadence is headquartered in San Jose, CA. The company serves industries such as semiconductors, automotive, aerospace and defense, consumer electronics, and telecommunications. Cadence’s offerings include tools for designing integrated circuits, systems on chips (SoCs), printed circuit boards (PCBs), and complete electronic systems. As of 2024, Cadence reported annual revenue of approximately $4.64 billion and employed around 12,703 people worldwide. The company’s comprehensive solutions support the development of advanced electronic products across various sectors.